This is a question I hear often in clinic, and the honest answer has more nuance than a one-line rule.
There is an important distinction between commercial "detox" products and classical Ayurvedic purification therapy — the latter is a supervised medical process with pre-assessment, a defined protocol, and monitored recovery, not a fixed-duration tea or juice cleanse.
Not everyone is a suitable candidate for intensive purification at a given time — pregnancy, certain acute illnesses, and significant debility are all reasons I would postpone or modify a protocol rather than proceed regardless.
Done properly and under supervision, purification therapy can meaningfully improve chronic conditions; done as a generic package without individual assessment, it can do more harm than good.
Every patient's presentation is different, so this is general clinical guidance rather than a substitute for an individual consultation — Dr Arjun Mehta, Dr, would want to examine your specific history before recommending a protocol.